At least three Nedbank Cup last-16 matches will pit Premier Division clubs against each other as confirmed during the draw held in Johannesburg on Monday evening.
Swallows FC are going to welcome Royal AM at home while TS Galaxy clash with Baroka FC and Marumo Gallants face Orlando Pirates.
Mamelodi Sundowns are at home to amateur side Mathaithai FC from the Free State and Platinum City Rovers face three-time Nedbank Cup champions SuperSport United.
Meanwhile, Sinenkani FC will clash against Tshakhuma Tsha Madzivhandila with Summerfield Dynamos welcoming Black Eagles FC and Venda Football Academy tackling the University of Pretoria.
Dates and venues of the quarter-final matches will be confirmed later.