Orlando Pirates will face Siwelele FC in the first round of the Carling Black Label Cup as confirmed by the draw, which was held at the FNB Stadium in Nasrec, Johannesburg, on Monday afternoon.
On the other hand, Limpopo side and defending champions Magesi FC start the defence of their title with an away clash against AmaZulu.
After they met in the semi-finals last season, Mamelodi Sundowns and Marumo Gallants will meet yet again in the first round of the competition while Stellenbosch FC, champions two seasons ago, will be at home to Kaizer Chiefs.
Orbit College are going to welcome TS Galaxy, runner-up two seasons ago, and other newcomers Durban City are up against Polokwane City.
Richards Bay FC, who were semi-finalists in the last two editions of the competition, will face Chippa United and Lamontville Golden Arrows will be home to Sekhukhune United.
The first round of the competition will start on Saturday, 4 October, and the venues will be confirmed later.